A Certain Scientific Railgun manga volume 6 features story by Kazuma Kamachi and art by Motoi Fuyukawa.

Despite Misaka's tireless efforts and her explosive confrontation with ITEM at Academy City's Pathology Analysis Laboratory, progress on the "Sisters" cloning project hasn't missed a beat. Something big is behind the Sisters, and the deeper Misaka digs, the less she understands.

Out of options, Misaka finally resorts to a deadly gambit against the project's crowing achievement: the Accelerator himself. In her darkest moment, an unlikely hero emerges who may turn out to be Misaka's only salvation.